Research Scientist, Discovery - New Haven, NJ
Job Type: Fulltime
Job Description:
Biotechnology company developing novel, proprietary vaccines. The company’s breakthrough vaccines are based on its Toll-like receptor (TLR) technology platform, which dramatically improves vaccine immunogenicity and efficacy.
Responsibilities:
We are looking for a candidate who can lead a project focused on the discovery of novel TLR agonists. The individual will be responsible for selection and affinity maturation of novel peptide/protein ligands using phage display and protein evolution technologies. This will include developing selection strategies, executing screens, analyzing hit sequence results, cloning and expressing the selected candidates.
Other responsibilities include construction of affinity maturation libraries as well as development and running screening assays.
The individual should be creative and have an established record of independent research accomplishments in recombinant protein engineering.
Requirements
Qualifications:
Ph.D. in Immunology, Molecular Biology, Virology or related field.
Intimate knowledge of cutting-edge molecular biology and bioinformatics tools and strategies for protein evolution.
Experience using phage display in a screening program is highly desired.
Experience in mammalian cell culture, cell-based and biochemical assay development, automation and screening is an advantage.
A track record of patent applications and peer-reviewed publications.
Salary Range: $75,000 - $80,000
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